Welcome to Professor Thayer's Lab
The research conducted at the Thayer laboratory contributes to the advancement of public health. The laboratory's work will provide an inexpensive, robust, and innovative method for the development of a new class of drugs. The broad positive impact on all diseases involving protein regulation including cancer would provide an equitable treatment for anyone being treated for a disease involving protein regulation. Free energy landscapes in vectors based on Molecular Dynamics simulations contribute to an innovative approach to allosteric drug design that will supersede expensive wet lab technology. MD computational methods have significant advantage of molecular insight into the mechanism of action. Through the understanding of the p53 protein and the use of Molecular Dynamic simulations, will enable widespread applications of rational design drug discovery methods to many proteins and thereby to many diseases, leading to enhanced health, longer life, and reduction of illness.